This study examined the effect of Chemistry teachers on the performance of students in senior secondary school in Kwara State, Nigeria. The target population for the study was all Chemistry teachers in Kwara State, Nigeria, three hundred and eighty-two (382) public senior secondary school and three hundred and sixty-two (362) private schools. The researcher designed teachers' questionnaire was administered to one hundred and firth-five (155) teachers selected from thirty (30) public and twenty (20) private secondary schools in Kwara State. Researcher-designed validated questionnaire was used to elicit information from the respondents on the teachers 'influence towards the performance of students in senior secondary schools. Three research questions were answered and two hypotheses were tested. Percentage, t-test statistics and ANOVA were used to analyze the data collected. The finding of this study revealed that effect of Chemistry teachers towards the performance of students in senior secondary school in Kwara State, Nigeria was significant based on their responses and academic qualification but not significant on gender. Based on the findings of this study, it is hereby recommended that; Report of this study implies that educational administrators must ensure adequate and sufficient moral support for chemistry teachers. This will enable teachers to become more committed in the discharge of their duties. Chemistry teachers should get teacher training, should be given due respect and should be paid according to their qualifications and abilities among others.Keywords:
Chemistry teachers, Gender, Academic qualification, students in senior secondary schools.